Jack Andraka – A Novel Paper Sensor For The Detection Of Pancreatic Cancer

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[Jack Andraka - A Novel Paper Sensor For The Detection Of Pancreatic Cancer]

[Announcer] Source: LYBIO.net
And the winner of the $75,000 dollar 2012 Gordon E. Moore Award in the category of medicine and health sciences ( ) Jack Thomas Andraka.

[Announcer]
And now ladies and gentlemen it is my honor to present to you the top award winners of the 2012 Intel International Science Fair ( ).

[Jack Thomas Andraka]
I did not think I was going to win a single award but it – it’s just unbelievable, I can not believe this is happening to me. This means so much, this was my childhood dream, I – I was like I always wanted to go to Intel ISEF and I would look through the magazines at those people staring up into the sky majestically and I’m just like oh if only I could be there one day and now I am and I’m just so thrilled.

[Questions]
It has been applied only for this particular bio-marker or for other bio-markers?

[Jack Thomas Andraka] Source: LYBIO.net
This is the very first time that this method – I actually thought up of this method entirely on my own I have pat- patented the entire method.

[Question]
And which lab did you do this in?

[Jack Thomas Andraka]
Doctor Maitra’s lab of Johns Hopkins University but I did think of it all my own.

[Jack Andraka] Source: LYBIO.net
Hi I’m Jack Andraka from Crownsville Maryland and I’m fifteen I’m a freshman. So basically what I’ve done here is created a paper sensor that can detect a wide array of diseases and some noble examples are pancreatic cancer, ovarian cancer and lung cancer. And all these are life threatening diseases and it’s really crucial to detect them in their early stages where survival rates are at their highest. And I focused specifically on pancreatic cancer in this case because due to its extremely low survival rates.

A Novel Paper Sensor For The Detection of Pancreatic Cancer.
(Introduction) (Methodology) (Data Analysis)

[Jack Andraka] Source: LYBIO.net
So, what I did; is create this paper sensor and it basically has single wall carbon nanotubes which are
atom thick tubes of carbon mixed with anti-bodies to this one cancer bio-marker called Mesothelin. An anti-body is basically a molecule that bindes specifically to one other molecule. So, what happens is; when I compared it, to the current gold standard of protein detection called called ELISA (enzyme-linked immunosorbent assay), it was actually 168 times faster, over 26,000 times less expensive and over 400 times more sensitive. And what I found is that my sensor in a blind study it actually had a 100% correct diagnosis, in diagnosing pancreatic cancer and could diagnose the cancer before it actually became invasive.

I did not expect for it to be this good at detecting Pancreatic cancer, anti-bodies and stuff so – I was blow away by how sensitive it was.

I actually got into this kind of work because my uncle he died due to pancreatic cancer it metastasized and I got interested in early diagnosis and I found the blood tests where the only practical way to detect it in routine screening, so then I got interested in Mesothelin and actually loved single wall carbon nanotubes, they are the superheros of material science and so then I was just thinking how I could apply them here and it came to me one day in biology class.

I am incredibly excited, it’s like the Olympics of science fair, it’s amazing to be here, even if I don’t get a prize.

Jack Andraka – A Novel Paper Sensor For The Detection Of Pancreatic Cancer. A Novel Paper Sensor For The Detection of Pancreatic Cancer. (Introduction) (Methodology) (Data Analysis). Complete Full Transcript, Dialogue, Remarks, Saying, Quotes, Words And Text.